• Overview
  • How to order a test
  • National test directory
  • Getting the results
  • 100k guidance for clinicians
  • Educational resources
  • Education & Training events calendar

Genomic medicine is now part of mainstream NHS care and all healthcare professionals (not just genetics specialists) need to have a good understanding of its relevance. The pathway below outlines the Whole Genome Sequencing (WGS) pathway. 

Clinician requests a test from the National Test Directory by completing a Test Order Form and sending this to the GLH with the Patient Choice form and appropriate samples.
The GLH receive the forms and samples. The information from these forms are entered into the NGIS Test Ordering System. DNA is extracted from the samples.
The GLH sends the extracted DNA to be plated and sequenced. The genome data is quality checked and identified variants prioritised before the data is returned to the GLH.
The GLH performs interpretation and issues a NHS Genomic Report to the ordering clinician.
Resource library- Professionals

Library of resources

Carefully created and curated for healthcare professionals across the region to make the best use of genomics in their practice.

Calendar- Professionals

Education & events calendar

Our programme of genomics education for healthcare professionals is delivered through a mixture of face-to-face and online events.

We want to hear from you!

How to order a test

Genomic testing in the NHS is provided through a national testing network of seven Hubs. The South East Genomic Laboratory Hub coordinates genetic and genomic testing for the South London, Kent, Surrey and Sussex region. The tests will be aligned to the Cancer and Rare Disease National Genomic Test Directories. These directories specify which genomic tests are commissioned by the NHS in England, the technology by which they are available, the patients who are eligible to access the tests, and the healthcare professionals who can order them.

Follow the links below to find out more and start the referral process:

I want to order a
Cancer test

This link will take you to the available cancer tests, sample requirements and test request forms.
Click Here

I want to order a
Non-Cancer test

This link will take you to the available non-cancer tests, sample requirements and test request forms.
Click Here

Documents and forms

Shortcut to the GLH test request forms

National test directory

The National Genomic Test Directory

The 2020/2021 National Genomic Test Directory specifies which genomic tests are commissioned by the NHS in England, the technology by which they are available, and the patients who will be eligible to access to a test. 

National Genomic Test Directory

The 2020/2021 National Genomic Test Directory for rare and inherited disorders and cancer.

Getting results

All genetic and genomic test results will be returned by the South East Genomic Laboratory Hub after appropriate interpretation and analysis has been completed. These reports will be returned directly to the ordering clinician, unless instructed otherwise.

100k guidance for clinicians

A big thank you to all the healthcare professionals in the South London, Kent, Surrey and Sussex region who helped recruit over 2000 Cancer participants and nearly 4000 Rare Disease participants and their families to the Project. Recruitment to the Project has now come to an end and our current focus is on returning the results of the project to patients. Your continued cooperation and support are critical in ensuring this happens.


Referring clinicians may be invited to a Genomic MDT meeting to review the results and discuss next steps for the patient. Depending on this discussion, more work may be required before the final result can be returned to the referring clinician (i.e. further analysis and validation of the findings).

In some cases an MDT discussion may not be appropriate and the report may be issued directly after the analysis at the lab. The referring clinician is then responsible for discussing the result with the patient.

Information for healthcare professionals on the 100,000 Genomes Project can be found on the Genomics England website:

Education & Training events calendar

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Events for June 2021

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#GenomicsConversation week of action 2021

#GenomicsConversation week of action 2021

RCNi webinar series: From Niche to Necessity: Genomics in routine care

#GenomicsConversation week of action 2021

#GenomicsConversation week of action 2021

#GenomicsConversation week of action 2021

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South East Genomics

Welcome to our new home

We have recently changed our name from the NHS London South Genomic Laboratory Hub to the NHS South East Genomic Laboratory HubWe think it better reflects the region we cover!

Hello! Welcome to the South East GLH website. The site is not fully supported in older versions of Internet Explorer. To get the best experience, we recommend that you use Google Chrome or Firefox to browse the site.

With any Whole Genome Sequencing (WGS) test ordered, a Record of Discussion (RoD) form will also need to be submitted. This document is to record the patient’s consent for genomic testing and their choice on taking part in research. Guidance on the patient choice conversation can be found here
This RoD form will be available for clinicians to download from this webpage. Once completed with the patient, it can be send to the lab with the corresponding test order form and sample.
Tests available to order will be listed in the National Genomic Test Directory. A test order form will soon be made available for clinicians on this webpage to download and complete. This form will include the address of the laboratory that the appropriate sample and completed form needs to be sent to.
Until the new Genomic Laboratory Service goes live, please continue to follow existing test order processes.
Later this year, the online test ordering tool for Whole Genome Sequencing will be integrated into the National Genomics Informatics System (NGIS) and clinicians will be able to search or filter to find a clinical indication, confirm eligibility criteria and start the test request process for their patient.