Clinical Indication ID & Name
Any patient receiving solid organ transplantation (only in cases where passenger lymphocyte syndrome is suspected)
Test Group
Solid Tumours (Adult)
Specialties
Test code
M242.1
Test name
STR Testing
Target genes
Test scope
Short tandem repeat analysis
Test method/ technology
Complex targeted mutation testing
Optimal Family Structure
n/a
Eligibility Criteria
Patient is post-solid organ transplant and the treating clinician has concerns they have developed passenger lymphocyte syndrome based on their clinical presentation; i.e. they have developed cytopenias not wholly explainable via other causes.
Allogeneic transplant where chimerism knowledge will aid patient management.
Test code
M242.2
Test name
Sex chromosome FISH
Target genes
X chromosome, Y chromosome
Test scope
Copy number variant detection to genomewide resolution
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Patient is post-solid organ transplant and the treating clinician has concerns they have developed passenger lymphocyte syndrome based on their clinical presentation; i.e. they have developed cytopenias not wholly explainable via other causes.
Commissioning group
n/a
Overlapping idications
n/a
Address for samples/request forms
Cancer Genetics
Genetics Laboratories
5th Floor Tower Wing
Guy’s Hospital
Great Maze Pond
London
SE1 9RT
Contact with queries
Supporting documents
Cancer WGS Clinician pack
Education resources
n/a
Turn around times
n/a
Request form download
Consent record
See consent guidance in test request form
Sample requirements
Samples may be rejected for the following reasons: 1.Samples and request form do not show at least three identical patient identifiers 2.The sample is in the incorrect collection media 3.The request form is not sufficiently completed 4.The sample is not of sufficient volume 5.The sample is too old