Order or find a test

The National Genomic Test Directories specify which genomic tests are commissioned by the NHS in England, to be delivered by Genomic Laboratory Hubs.

Clinical Indication ID & Name

R454

Mavacamten for treating symptomatic obstructive hypertrophic cardiomyopathy

Test Group

Specialties

Test code

R454.1

Test name

Mavacamten for treating symptomatic obstructive hypertrophic cardiomyopathy

Target genes

Test scope

*2, *3 and *17 alleles

Test method/ technology

Targeted variant testing

Optimal Family Structure

n/a

Eligibility Criteria

Testing Criteria
Testing is available to patients with:
1. symptomatic obstructive hypertrophic cardiomyopathy who have a New York Heart Association class of 2 to 3 AND
2. are eligible for treatment with mavacamten in line with NICE TA 913 (where mavacamten is an add on to individually optimised standard care that includes beta blockers, non-dihydropyridine calcium-channel blockers or disopyramide, unless these are contraindicated).
Where in Pathway
At prescribing decision
Requests for this test will only be accepted from centres that are commissioned to prescribe Mavacamten

Commissioning group

n/a

Overlapping idications

n/a

Address for samples/request forms

Contact with queries

Supporting documents

n/a

Education resources

n/a

Turn around times

n/a

Consent record

See consent guidance in test request form

Sample requirements

n/a