Clinical Indication ID & Name
Patient receiving solid organ transplantation (only in cases where passenger lymphocyte syndrome is suspected)
Test Group
Core/Specialised
Specialties
Test code
R428.1
Test name
N/A
Target genes
Relevant gene(s) or loci
Test scope
n/a
Test method/ technology
STR testing
Optimal Family Structure
n/a
Eligibility Criteria
Patient is post-solid organ transplant and the treating clinician has concerns they have developed passenger lymphocyte syndrome based on their clinical presentation; i.e. they have developed cytopenias not wholly explainable via other causes.
Allogeneic transplant where chimerism knowledge will aid patient management.
Test code
R428.2
Test name
N/A
Target genes
Sex chromosomes
Test scope
n/a
Test method/ technology
FISH
Optimal Family Structure
n/a
Eligibility Criteria
Patient is post-solid organ transplant and the treating clinician has concerns they have developed passenger lymphocyte syndrome based on their clinical presentation; i.e. they have developed cytopenias not wholly explainable via other causes.
Allogeneic transplant where chimerism knowledge will aid patient management.
Commissioning group
Core/Specialised
Overlapping idications
• M242 Any patient receiving solid organ transplantation – same test duplicated in the cancer Test Directory
Address for samples/request forms
Genetics Laboratory
5th Floor Tower Wing
Guy’s Hospital
London
SE1 9RT
Contact with queries
Supporting documents
n/a
Education resources
n/a
Turn around times
All our turnaround times are listed on our specific turn around page https://southeastgenomics.nhs.uk/professionals/service-turn-around-times/
Request form download
Consent record
See consent guidance in test request form
Sample requirements
Samples may be rejected for the following reasons: 1.Samples and request form do not show at least three identical patient identifiers 2.The sample is in the incorrect collection media 3.The request form is not sufficiently completed 4.The sample is not of sufficient volume 5.The sample is too old