Loading Events

« All Events

  • This event has passed.

National pathology workshops: Lynch Syndrome

November 8 2022 @ 1:00 PM - 2:00 PM

|Recurring Event (See all)

One event on November 8 2022 at 1:00 PM

Lynch syndrome (LS) is an inherited condition caused by pathogenic variants in DNA genes which result in an increased risk of colorectal, endometrial, and other cancers. LS affects approximately 1 in 300-1 in 400 people, with 200,000-300,000 people likely to have this condition in the UK. It is estimated that only 5% of people with LS have been diagnosed with this condition.


NICE guidelines recommend universal testing for LS in people with colorectal (CRC) [DG27] and endometrial cancer [DG42].


These national workshops will outline the responsibilities of pathologists in the Lynch syndrome testing pathway. All pathologists, biomedical scientists and any other pathology department or Colorectal and Gynae cancer MDT staff are welcome.


Please note each workshop will cover the same content.


Topics and speakers:

1) An introduction to Lynch syndrome and the national NHS GMS transformation project

Kevin Monahan, Consultant Gastroenterologist at St Mark’s Hospital and Co-Chair of the national NHS GMS Lynch Syndrome Oversight Group

2) The Lynch syndrome testing pathway and the role of the pathologist

Nick West, Associate Professor of Pathology and Honorary Consultant in Gastrointestinal and Molecular Pathology, Leeds Teaching Hospitals NHS Trust

3) Panel Q&A


With any Whole Genome Sequencing (WGS) test ordered, a Record of Discussion (RoD) form will also need to be submitted. This document is to record the patient’s consent for genomic testing and their choice on taking part in research. Guidance on the patient choice conversation can be found here
This RoD form will be available for clinicians to download from this webpage. Once completed with the patient, it can be send to the lab with the corresponding test order form and sample.
Tests available to order will be listed in the National Genomic Test Directory. A test order form will soon be made available for clinicians on this webpage to download and complete. This form will include the address of the laboratory that the appropriate sample and completed form needs to be sent to.
Until the new Genomic Laboratory Service goes live, please continue to follow existing test order processes.
Later this year, the online test ordering tool for Whole Genome Sequencing will be integrated into the National Genomics Informatics System (NGIS) and clinicians will be able to search or filter to find a clinical indication, confirm eligibility criteria and start the test request process for their patient.