Management of Familial Hypercholesterolaemia in General Practice eLearning course

Created by the Royal College of General Practitioners (RCGP), this course consists of two modules. Module 1 provides GPs and other Health Care Professionals with information about the causes and consequences of FH, how they can identify those in their practice most likely to have FH, and how these patients and their relatives should be managed. Module 2 covers the genetic causes of FH in more detail, suggests new search algorithms to help in patient identification, and describes novel lipid-lowering agents that are in development.

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The primary prevention of cardiovascular disease (CVD) is one of the most important aspects of primary care and is particularly important for those patients with familial hypercholesterolemia (FH). As the prevalence of heterozygous FH in the UK population is approximately 1 in 250, a typical practice with 10,000 patients might have up to 40 patients with a significantly increased risk of premature heart disease.

The condition is significantly underdiagnosed, and the 2017 NICE FH guideline has recommended case finding in primary care using electronic records as an acceptable and highly cost effective method for individual practices to identify patients who so far have not had the benefit of treatment. The NHS 2019 long-term plan has set an ambition to identify 25% of the predicted FH patients in the next 5 years, and achieving this will depend heavily on GP input.

This course was created by the Royal College for General Practitioners (RCGP). A grant was received by North Thames Genomic Laboratory Hub (based at GOSH), South East Genomic Medicine Service Alliance and Health Education England for the production of this resource. Editorial and content decisions were made solely by the RCGP.

Created by the Royal College of General Practitioners (RCGP), this course consists of two modules. Module 1 provides GPs and other Health Care Professionals with information about the causes and consequences of FH, how they can identify those in their practice most likely to have FH, and how these patients and their relatives should be managed. Module 2 covers the genetic causes of FH in more detail, suggests new search algorithms to help in patient identification, and describes novel lipid-lowering agents that are in development.