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Order or find a test

The National Genomic Test Directories specify which genomic tests are commissioned by the NHS in England, to be delivered by Genomic Laboratory Hubs.

Clinical Indication ID & Name

M244

In all tumours eligible for NTRK1/2/3 testing

Test Group

Solid Tumours (Adult)

Specialties

Test code

M244.1

Test name

FISH

Target genes

NTRK1/2/3

Test scope

Structural variant detection

Test method/ technology

FISH

Optimal Family Structure

n/a

Eligibility Criteria

To be performed in Salvage pathway and when samples are not suitable for panel testing or NGS panel testing has failed.
NB will be subject to close audit

Commissioning group

n/a

Overlapping idications

n/a

Address for samples/request forms

Cancer Genetics
Genetics Laboratories
5th Floor Tower Wing
Guy’s Hospital
Great Maze Pond
London
SE1 9RT

Contact with queries

gst-tr.gtabsoutheastglh@nhs.net

Supporting documents

n/a

Education resources

n/a

Turn around times

All our turnaround times are listed on our specific turn around page https://southeastgenomics.nhs.uk/professionals/service-turn-around-times/

Request form download

Solid Tumour Request Form WGS Record of Discussion

Consent record

See consent guidance in test request form

Sample requirements

Sample Requirements Each sample must be sent labelled with 3 patient identifiers and must state the sample type clearly on the sample container. Sample Rejection Samples may be rejected for the following reasons: 1. Samples and request form do not show at least three identical patient identifiers 2. The sample is in the incorrect collection media 3. The request form is not sufficiently completed 4. The sample is not of sufficient volume 5. The sample is too old|Sample Storage and Volume Required: FFPE tissue sections – 3-4µm sections on unstained Apes slides with appropriate IHC/H&E slide for correlation. Please see referral form for an indication of how many slides to include for testing (additional slides are advised to enable repeat testing in case of suboptimal hybridisation). Storage, sample packing and transportation: N/A Patient/Clinician Instructions: N/A Factors affecting performance of test/interpretation of results: It is essential to include an H&E or appropriate immuno stained slide, where areas of tumour are not easily identifiable these should be clearly marked on the slide. Cases referred without an H&E/immuno slide will not be analysed until this is provided.