Clinical Indication ID & Name
Recurrent miscarriage, products of conception not available – parental karyotype
Test Group
Core
Test code
R464.1
Test name
Recurrent miscarriage – karyotype
Target genes
Test scope
copy number variant detection to genomewide resolution and structural variants
Test method/ technology
Karyotype
Optimal Family Structure
n/a
Eligibility Criteria
Testing Criteria
. Recurrent miscarriage (defined as three or more miscarriages):
• where testing of the pregnancy loss has not been possible due to an unsuitable/failed sample e.g. no fetal material/MCC/fixed in formalin, and no previous losses have been successfully tested and reported. Note that although parental karyotype analysis is available following a failed test, this is of limited utility and the most informative pathway is to test any subsequent pregnancy loss.
Recurrent miscarriage (five or more pregnancy losses):
• Where none of the previous losses have been successfully tested and reported e.g. biochemical pregnancies, no products available for testing
Where in Pathway
At presentation
Commissioning group
n/a
Overlapping idications
n/a
Address for samples/request forms
Contact with queries
Supporting documents
n/a
Education resources
n/a
Turn around times
n/a
Request form download
n/a
Consent record
n/a
Sample requirements
n/a