SE-HMDS: March Newsletter


Dear Colleagues,

We hope you are all keeping well as we come out of the second wave of the COVID-19 pandemic.

The SE-HMDS team would like to share some news and updates with you.

New request form
A new version of the SE-HMDS request form is available. It now incorporates all the tests outlined in the National Genomic Test Directory. Please do make sure you fill out the patient and clinical details as completely as possible, including specimen type and NHS number. It‘s particularly important to include the NHS number as that will be the key search field when the web based lookup for external referrers is a launched. The form is available on the Viapath and SE-GLH websites, please dispose of any old versions you may have printed.

In line with NHSE guidance its essential all genomic Haemato-Oncology tests including whole genome sequencing should be sent to the SE-HMDS central specimen reception at King’s College Hospital, Denmark Hill site. This allows a complete integrated report and better support for MDT meetings.

Lymphoid Gene panel
The lymphoid gene panel is now available to request. The panel contains genes relevant to non-Hodgkin lymphomas, CLL, myeloma, acute lymphoblastic lymphomas and histiocytic disorders. The genes included are outlined in the table below. Samples will be run using the whole panel but only mutations in genes relevant to the referral diagnosis will be reported. As we get used to using this new testing, the HMDS consultants would be happy to discuss appropriate test requesting at MDM meetings or on an individual case basis.

ALLPlasma cell neoplasmsB cell lymphomasCLL/Hairy cell leukaemiaT cell lymphoma/leukaemiaHistiocytic disorders

Funding of genomics tests
Genomics tests included in the National Genomic Test Directory will now be funded centrally through payments to the Genomic Laboratories directly from NHSE rather than provider to provider payment.

Customer survey notification
We would be very grateful if you could fill out this short user survey. We greatly value your feedback as we strive to continually improve the services we provide to meet your clinical requirements. This will come via a separate email.

Case of the week
Case of the week presentations restart on Friday 5th March 2021 8.15am via Teams. You need to be a member of the TEAM called Case of the Week. If you need to be added please email We are only able to add email addresses.
Looking forward to seeing you there.

Coming soon
Whole gene sequencing for acute leukaemia is slowly ramping up BUT we are not quite ready to receive your patients’ samples yet. We will be in touch very soon with a go live date.

We are working hard on bringing you direct access to your patient’s SE-HMDS results by making our internal IT system available externally through web browser access. This will require the set-up of individual usernames and passwords for clinical staff. We will be in touch shortly with these set up details.

With best wishes for the coming month

Dr Debby Yallop, Dr Shireen Kassam, Dr Guy Hannah and Dr Robin Ireland
SE-HMDS Consultants

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With any Whole Genome Sequencing (WGS) test ordered, a Record of Discussion (RoD) form will also need to be submitted. This document is to record the patient’s consent for genomic testing and their choice on taking part in research. Guidance on the patient choice conversation can be found here
This RoD form will be available for clinicians to download from this webpage. Once completed with the patient, it can be send to the lab with the corresponding test order form and sample.
Tests available to order will be listed in the National Genomic Test Directory. A test order form will soon be made available for clinicians on this webpage to download and complete. This form will include the address of the laboratory that the appropriate sample and completed form needs to be sent to.
Until the new Genomic Laboratory Service goes live, please continue to follow existing test order processes.
Later this year, the online test ordering tool for Whole Genome Sequencing will be integrated into the National Genomics Informatics System (NGIS) and clinicians will be able to search or filter to find a clinical indication, confirm eligibility criteria and start the test request process for their patient.